Son Heung-min (£8.8m) makes his third start in a row since returning from the Asian Cup last month.
The South Korean has been averaging 7.1 points per game at Wembley since Gameweek 13 and carries the added responsibility of being the most transferred-in player ahead of Gameweek 26.
Over 550,000 managers opted to sign Son following the conclusion of Double Gameweek 25.
This time he is joined in the starting line-up by the returning Fernando Llorente (£5.7m) after he was benched against Newcastle last time out.
Christian Eriksen (£9.3m) keeps his place in the midfield but is joined by youngster Oliver Skipp (£4.5m).
Meanwhile, Erik Lamela (£6.1m) misses out on the match entirely with a reported back spasm.
In defence, Jan Vertonghen (£5.9m) and Davinson Sánchez (£5.8m) are selected in a back four, with Toby Alderweireld (£6.0m) on the bench.
Claude Puel has made a brave call for Leicester’s visit to Wembley as he has left Jamie Vardy (£8.8m) on the bench.
Demarai Gray (£5.4m) leads the line for the Foxes, while Youri Tielemans (£6.0m) makes his debut in central midfield.