Alexis Sánchez (£10.0m) has come into the Manchester United side for his first start since Gameweek 29.
The Chilean international has been in a front-three, but his position within that is yet to be confirmed with Marcus Rashford (£7.3m) also in the side.
The Englishman had been a fitness doubt ahead of Gameweek 37 but has overcome it, much to the delight of his 21.2% ownership.
Paul Pogba (£8.5m) is the only Manchester United player in more squads for Gameweek 37, so there will be plenty of interest in both of those two.
Meanwhile, his attacking partner Sánchez is one for those chasing extreme deficits in their mini-leagues and overall rankings.
He sits in just 1.2% of teams for the trip to Huddersfield and still remains a risk despite his start. The last time he featured from the beginning, Sánchez lasted just 51 minutes.
Elsewhere in the Manchester United team, there were welcome starts for those invested in their defence.
Luke Shaw (£5.1m) is the most popular, owned by 7.1%, while Victor Lindelöf (£5.2m) features alongside Phil Jones (£5.1m), who overcame a fitness doubt to start.
Meanwhile, Chelsea are also in action at the same time, with Eden Hazard (£10.9m) the most captained player of Sunday’s games.
410,000+ managers have trusted him with the armband after three double-figure hauls in his last four home matches.
He has been stationed on the left of an attacking front-three for Chelsea, with Gonzalo Higuaín (£9.0m) and Pedro (£6.2m) alongside him.
Owners of Chelsea defenders may be a little cautious given that Troy Deeney (£5.8m) is back in the Watford side.
He returns from a three-match suspension to play alongside Gerard Deulofeu (£5.7m) in a front-two, who has six goals and an assist in his last five away matches.
Chelsea XI: Kepa, Azpilicueta, Luiz, Christensen, Alonso, Kante, Jorginho, Kovacic, Hazard, Higuain, Pedro.
Watford XI: Foster, Femenia, Mariappa, Cathcart, Holebas, Doucoure, Hughes, Chalobah, Pereyra, Deulofeu, Deeney.
Huddersfield XI: Lössl; Bacuna, Schindler, Kongolo, Durm; Mbenza, Mooy, Hogg, Löwe; Pritchard; Grant.
Man United XI: De Gea; Shaw, Jones, Lindelöf, Young; Pogba, McTominay, Matic; Rashford, A Sánchez, Mata.