The final match of Gameweek 18 takes place at the Tottenham Hotspur Stadium, with Chelsea the visitors to north London.
Kick-off is at 16:30 GMT.
The team news is straightforward from a Spurs perspective: Jose Mourinho has named an unchanged side for the third game running.
The Chelsea starting XI requires a bit more explanation, however.
Frank Lampard has benched Christian Pulisic (£7.3m) for the first time in the Premier League since Gameweek 9, with Jorginho (£5.0m) and the injured Emerson Palmieri (£5.5m) also making way from the side that lost to Bournemouth.
Marcus Alonso (£6.0m) gets his first start since Gameweek 10, with Mateo Kovacic (£5.3m) and Fikayo Tomori (£4.8m) also recalled.
All of that would seem to suggest that Lampard has switched to a 3-4-3, with Tomori joining Kurt Zouma (£4.7m) and Antonio Rudiger (£6.0m) at centre-half.
Mason Mount (£6.5m) and Willian (£7.0m) appear to be flanking Tammy Abraham (£7.9m) in attack.
Mount, Pulisic and Abraham were three of the four most-sold FPL assets of Gameweek 18.
Lampard’s side have lost four of their last five Premier League games and haven’t kept a clean sheet on the road in 2019/20.
Spurs, by contrast, have won four of their five league games under Jose Mourinho since the ‘Special One’ first took charge a month ago.
Dele Alli (£8.8m), Son Heung-min (£10.1m) and Harry Kane (£10.9m) are averaging 8.0, 7.8 and 5.4 points per game respectively under their new manager.
Kane is the fourth-most-popular captaincy pick of Gameweek 18, while only three FPL assets were bought by more managers than Son in the run-up to this weekend.
Spurs XI: Gazzaniga, Aurier, Alderweireld, Sanchez, Vertonghen, Dier, Sissoko, Dele, Son, Lucas, Kane.
Chelsea XI: Arrizabalaga, Azpilicueta, Zouma, Tomori, Rudiger, Alonso, Kante, Kovacic, Willian, Mount, Abraham.
4 years, 4 months ago10 minutes left to brace Kane. I believe in you!