Pep Guardiola has rung the changes for the final match of Double Gameweek 30+, which kicks off at the Etihad at 20:00 BST.
Burnley are the visitors to Eastlands, where Manchester City defeated Arsenal five days ago.
There are only three surviving members of Guardiola’s starting XI from that 3-0 win over the Gunners, with Ederson (ÂŖ6.0m), David Silva (ÂŖ7.3m) and Riyad Mahrez (ÂŖ8.5m) keeping their places.
That means that Kevin De Bruyne (ÂŖ10.6m) and Raheem Sterling (ÂŖ11.7m) are both rotated out of the side, with the two premium Fantasy Premier League midfielders only among the substitutes.
Sergio Aguero (ÂŖ11.8m) gets his chance up front, meanwhile, with Gabriel Jesus (ÂŖ9.6m) making way.
Aymeric Laporte (ÂŖ6.3m), Kyle Walker (ÂŖ5.6m), Benjamin Mendy (ÂŖ5.5m), Ilkay Gundogan (ÂŖ5.2m) and Eric Garcia (ÂŖ4.5m) are the other City starters from midweek who drop out of the City line-up, with all bar the concussed Garcia on the bench.
Guardiola has changed his entire back four, with Joao Cancelo (ÂŖ5.1m), Oleksandr Zinchenko (ÂŖ5.2m), Fernandinho (ÂŖ5.1m) and Nicolas Otamendi (ÂŖ4.9m) tasked with keeping Burnley at bay.
Phil Foden (ÂŖ5.1m), Bernardo Silva (ÂŖ7.7m) and Rodri (ÂŖ5.5m) are also recalled further forward.
Sean Dyche’s side are missing the sidelined Chris Wood and Ashley Barnes (both ÂŖ6.1m), so Matej Vydra (ÂŖ5.3m) and Jay Rodriguez (ÂŖ5.7m) are paired together in attack for the visitors.
Josh Brownhill (ÂŖ4.8m) makes his first Premier League start, while Matthew Lowton (ÂŖ4.2m) returns from an enforced lay-off at right-back.
Not only are Burnley hit by injury, they are also without four players whose contracts are due to expire at the end of the month: Joe Hart (ÂŖ4.2m), Jeff Hendrick (ÂŖ5.4m), Aaron Lennon (ÂŖ4.6m) and Phil Bardsley (ÂŖ4.3m) are not even among the substitutes as doubts linger over their futures.
Four academy products make it onto Dyche’s under-strength bench as a result, with two goalkeepers among the seven substitutes that the Burnley boss has named.
De Bruyne is the most-captained player of Double Gameweek 30+ both overall and within the top 10k.
Over half of the managers inside the top 10,000 handed the armband to the Belgian.
Aguero was captained by 26.74% of those elite managers, meanwhile.
Manchester City XI: Ederson, Cancelo, Otamendi, Fernandinho, Zinchenko, Rodrigo, D Silva, Foden, Bernardo, Mahrez, Aguero.
Burnley XI: Pope, Lowton, Tarkowski, Mee, Taylor, Brownhill, Westwood, Cork, McNeil, Rodriguez, Vydra.
Double Gameweek 30+ FPL Lessons Learned
- Aston Villa 0-0 Sheffield United
- Manchester City 3-0 Arsenal
- Norwich City 0-3 Southampton
- Tottenham Hotspur 1-1 Manchester United
- Watford 1-1 Leicester City
- Brighton and Hove Albion 2-1 Arsenal
- West Ham United 0-2 Wolves
- Bournemouth 0-2 Crystal Palace
- Newcastle United 3-0 Sheffield United
- Aston Villa 1-2 Chelsea
- Everton 0-0 Liverpool
- Manchester City 5-0 Burnley

