Updated on a daily basis, this list of injuries and suspensions is designed to help with your team selection and transfers. This information is thoroughly researched but can never be 100% accurate. The Scout accepts no liability for any huge amounts of cash or mini-leagues lost as a result of acting upon any information found here.
- Injured
- Doubt (% Chance of Availability)
- Knock
- Available
- Disciplinary
- On Loan
- Unavailable
| Name | Club | Status | Return Date | Latest News | Last Updated |
|---|---|---|---|---|---|
 Bellerín (Héctor) | ARS | On Loan | 01/07/2022 | Joined Real Betis on a season-long loan [Source] | 31/08/2021 |
 Willian | ARS | Unavailable | Unknown | Transferred to Corinthians [Source] | 31/08/2021 |
 Kolasinac (Sead) | ARS | Injured | Unknown | Ankle injury Suffered a "significant" ankle injury in Bosnia and Herzegovina's match against Finland on 13/11. No timeframe has been put on his return. [Source] | 18/11/2021 |
 Leno (Bernd) | ARS | Doubt 75% | 11/12/2021 | Groin Injury Missed the match against Everton on 6/12 with groin tightness. [Source] | 06/12/2021 |
 Gabriel Martinelli | ARS | Doubt 75% | 11/12/2021 | Hamstring injury Substituted with hamstring pain against Everton on 6/12. [Source] | 07/12/2021 |
 Nelson (Reiss) | ARS | On Loan | 01/07/2022 | Joined Feyenoord on a season-long loan [Source] | 31/08/2021 |
 Rúnarsson (Rúnar) | ARS | On Loan | 01/07/2022 | Joined OH Leuven on a season-long loan [Source] | 31/08/2021 |
| Saliba (William) | ARS | On Loan | 23/05/2022 | Joined Marseille on loan for 2021/22. [Source] | 15/07/2021 |
 Smith-Rowe (Emile) | ARS | Doubt 75% | 11/12/2021 | Groin Injury Missed the match against Everton on 6/12 with groin tightness. [Source] | 06/12/2021 |
 Torreira (Lucas) | ARS | On Loan | 01/07/2022 | Joined Fiorentina on a season-long loan [Source] | 25/08/2021 |
| Bailey (Leon) | AVL | Injured | Unknown | Thigh injury Substituted with a quad muscle injury in the match against Man City on 1/12. Will be out for a "number of weeks" and won't return before Christmas. [Source] | 03/12/2021 |
 Guilbert (Frederic) | AVL | On Loan | 01/07/2022 | Joined Strasbourg on a season-long loan [Source] | 31/08/2021 |
 Trezeguet | AVL | Injured | 11/12/2021 | Lack of match fitness Recovered from a knee injury sustained against Liverpool on 10/4. Has completed a full week of training as of 26/11 and will play for the under-23s on 6/12 before being considered for a first-team return. [Source] | 30/11/2021 |
 Hourihane (Conor) | AVL | On Loan | 01/07/2022 | Joined Sheffield United on a season-long loan [Source] | 31/08/2021 |
 Ings (Danny) | AVL | Doubt 50% | 11/12/2021 | Muscle injury Ruled out of the Man City game on 1/12 with the recurrence of a muscle problem. Was given "every chance" to face Leicester on 5/12 but missed out. [Source] | 05/12/2021 |
 Targett (Matt) | AVL | Doubt 75% | 11/12/2021 | Head injury Substituted in the match against Man City on 1/12 after a bang on the head. His manager said he would "struggle" to recover in time for the Leicester match on 5/12 and he indeed missed out. [Source] | 05/12/2021 |
 Traore (Bertrand) | AVL | Injured | 26/12/2021 | Thigh injury Had been in line to make the matchday squad against West Ham on 31/10 but failed to feature and has been missing since. A recurrence of a thigh injury sustained in October is being reported. An update on 30/11 suggested he was aiming to return to training before Christmas. [Source] | 30/11/2021 |
| Ajer (Kristoffer) | BRE | Injured | 02/01/2022 | Hamstring injury Missed the defeat to Burnley on 30/10 with a hamstring injury. His manager subsequently ruled him out for up to two months. [Source] | 04/11/2021 |
| Canos (Sergi) | BRE | Suspended | 14/12/2021 | 1 Match Ban Suspended for one match after picking up his fifth booking of the season on 5/12. | 06/12/2021 |
| Josh Da Silva | BRE | Injured | Unknown | Hip injury Will miss the start of 2021/22 with a long-standing hip problem. No date has been placed on his recovery. [Source] | 12/08/2021 |
| Fosu-Henry (Tariqe) | BRE | Injured | Unknown | Hamstring injury It was revealed on 30/11 that he is sidelined with a hamstring injury. [Source] | 30/11/2021 |
| Gunnarsson (Patrik) | BRE | On Loan | 15/01/2022 | Joined Viking on loan until the end of 2021 [Source] | 30/08/2021 |
| Zanka | BRE | Injured | Unknown | Muscle injury Substituted in the match against Norwich on 6/11 with a muscle issue and has been missing since. Won't face Spurs on 2/12. [Source] | 30/11/2021 |
| Raya Martin (David) | BRE | Injured | 19/03/2022 | Knee injury Ruled out for four to five months on 26/10 after sustaining a serious ligament injury in his left knee. [Source] | 26/10/2021 |
| Toney (Ivan) | BRE | Injured | 18/12/2021 | Illness Missed the Leeds game on 5/12 after testing positive for Covid-19 the day before. Will definitely miss the Watford match on 10/12. [Source] | 08/12/2021 |
 Alzate (Steven) | BHA | Injured | Unknown | Ankle injury Suffered an ankle injury in the match against Crystal Palace on 27/9. Ruled out of the clash with Arsenal on 2/10. Has since undergone surgery and will be out for a lengthy period. [Source] | 21/10/2021 |
 Andone (Florin) | BHA | On Loan | 01/07/2022 | Joined Cadiz on a season-long loan [Source] | 23/08/2021 |
| Moises Caicedo | BHA | On Loan | 01/07/2022 | Joined Beerschot on a season-long loan [Source] | 31/08/2021 |
 Duffy (Shane) | BHA | Suspended | 15/12/2021 | 1 Match Ban Suspended for one match after picking up his fifth booking of the season on 4/12. | 04/12/2021 |
 Dunk (Lewis) | BHA | Doubt 25% | Unknown | Knee injury Missed the match against Southampton on 4/12 with a knee injury and his manager says he is "99%" sure he won't recover to face Spurs on 12/12. [Source] | 06/12/2021 |
 Jahanbakhsh (Alireza) | BHA | Unavailable | Unknown | Transferred to Feyenoord | 20/07/2021 |
| Karbownik (Michal) | BHA | On Loan | 01/07/2022 | Joined Olympiacos on a season-long loan [Source] | 01/09/2021 |
 Lallana (Adam) | BHA | Injured | 18/12/2021 | Calf injury Substituted with a muscle injury in the match against West Ham on 1/12. Ruled out for "a couple of weeks". [Source] | 06/12/2021 |
 Mat Ryan | BHA | Unavailable | Unknown | Transferred to Real Sociedad | 12/07/2021 |
| Sarmiento (Jeremy) | BHA | Injured | 03/05/2022 | Hamstring injury Substituted with a hamstring injury in the match against West Ham on 1/12. Expected out for three months. [Source] | 06/12/2021 |
 Trossard (Leandro) | BHA | Doubt 75% | 12/12/2021 | Arm injury Stretchered off in the match against Southampton on 4/12 with an elbow injury but his manager said afterwards that the issue is "not as bad as first thought". [Source] | 04/12/2021 |
| Veltman (Joël) | BHA | Doubt 75% | 12/12/2021 | Facial Injury Suffered a blow to the nose in the match against Southampton on 4/12 and had to be replaced. [Source] | 04/12/2021 |
 Webster (Adam) | BHA | Injured | 18/12/2021 | Calf injury Substituted with a muscle injury in the match against West Ham on 1/12. Ruled out for "a couple of weeks". [Source] | 06/12/2021 |
 Welbeck (Danny) | BHA | Injured | Unknown | Hamstring injury "Tweaked his hamstring" in the match against Crystal Palace on 27/9. Reported to be seeing a specialist as of 30/9 and didn't feature against Arsenal on 2/10. Has since undergone surgery and is set for a lengthy period on the sidelines. [Source] | 21/10/2021 |
| Zeqiri (Andi) | BHA | On Loan | 01/07/2022 | Joined Augsburg on a season-long loan [Source] | 30/08/2021 |
 Bardsley (Phillip) | BUR | Doubt 25% | 12/12/2021 | Muscle injury Has a "niggly" injury ahead of the Newcastle game on 4/12 and "probably" won't be involved. [Source] | 04/12/2021 |
 Barnes (Ashley) | BUR | Injured | Unknown | Thigh injury Has a "little niggle" ahead of the Crystal Palace match on 20/11 and missed out. The problem was later revealed to be a thigh tear and he now faces "weeks" on the sidelines. [Source] | 26/11/2021 |
| Cornet (Maxwel) | BUR | Doubt 75% | 12/12/2021 | Thigh injury Suffered a thigh strain in the match against Newcastle on 4/12 and will be assessed. [Source] | 04/12/2021 |
 Mee (Ben) | BUR | Doubt 75% | 12/12/2021 | Shoulder injury Missed the match against Newcastle on 4/12 with a shoulder problem. [Source] | 04/12/2021 |
 Peacock-Farrell (Bailey) | BUR | On Loan | 01/07/2022 | Joined Sheffield Wednesday on a season-long loan [Source] | 27/07/2021 |
 Stephens (Dale) | BUR | Doubt 25% | 12/12/2021 | Illness Missed the match against Wolves on 1/12 as he was observing the Covid-19 protocols. [Source] | 02/12/2021 |
 Abraham (Tammy) | CHE | Unavailable | Unknown | Transferred to AS Roma | 18/08/2021 |
 Ampadu (Ethan) | CHE | On Loan | 01/07/2022 | Joined Venezia on a season-long loan [Source] | 31/08/2021 |
 Batshuayi (Michy) | CHE | On Loan | 01/07/2022 | Joined Besiktas on a season-long loan [Source] | 18/08/2021 |
| Chalobah (Trevoh) | CHE | Injured | Unknown | Hamstring injury Substituted in the match against Watford on 1/12 with a suspected hamstring problem. His manager said afterwards that he was concerned about the injury. Won't face West Ham on 4/12 as assessment continues. [Source] | 03/12/2021 |
 Chilwell | CHE | Injured | 15/01/2022 | Knee injury Substituted in the Champions League win over Juventus on 23/11 with a partial injury to his ACL. Ruled out for six weeks on 26/11. A decision will then be made as to whether he can return to action or require surgery. [Source] | 26/11/2021 |
 Jorginho | CHE | Doubt 75% | 11/12/2021 | Back injury Will miss the Champions League tie against Zenit on 8/12 due to back pain. [Source] | 07/12/2021 |
 Giroud (Olivier) | CHE | Unavailable | Unknown | Transferred to AC Milan | 18/07/2021 |
 Kanté (N'Golo) | CHE | Injured | Unknown | Knee injury Substituted in the Champions League win over Juventus on 23/11 after twisting his knee. Initially ruled out for "days" or one week but his manager said on 4/12 that he wasn't sure when he'd back. [Source] | 04/12/2021 |
 Kovacic (Mateo) | CHE | Injured | 19/12/2021 | Illness Tested positive for Covid-19 on 6/12. [Source] | 07/12/2021 |
 Emerson | CHE | On Loan | 01/07/2022 | Joined Lyon on a season-long loan [Source] | 19/08/2021 |
| Andersen (Joachim) | CRY | Doubt 50% | 12/12/2021 | Hamstring injury Missed the match against Aston Villa on 27/11 with a reported hamstring problem and won't recover in time for the Leeds game on 30/11. Will be monitored on a daily basis thereafter and hasn't completely been ruled out of the Man Utd match on 5/12. [Source] | 05/12/2021 |
| Ferguson (Nathan) | CRY | Injured | Unknown | Lack of match fitness Recovered from an Achilles injury that kept him out for six months and returned to training over the November international break. Still some way from a playing return. [Source] | 19/11/2021 |
 McArthur (James) | CRY | Injured | 12/12/2021 | Hamstring injury Ruled out of the Burnley game on 20/11 with a hamstring problem. Will be monitored on a weekly basis thereafter. Still sidelined as of 3/12 but back in training. [Source] | 03/12/2021 |
 Bernard | EVE | Unavailable | Unknown | Transferred to Sharjah FC | 23/07/2021 |
| Broadhead (Nathan) | EVE | On Loan | 01/07/2022 | Joined Sunderland on a season-long loan | 17/08/2021 |
 Calvert-Lewin (Dominic) | EVE | Injured | 26/12/2021 | Thigh injury Sustained a quadriceps injury in the match against Brighton on 28/8. Everton confirmed on 17/10 that there had been a setback in his recovery. Still sidelined as of 3/12 and will miss a further two weeks "minimum". [Source] | 03/12/2021 |
 Davies (Tom) | EVE | Injured | Unknown | Knee injury Media reports on 16/11 suggest that he will be sidelined with a knee injury for a number of weeks. That news was confirmed by Everton on 19/11. [Source] | 19/11/2021 |
 Kean (Moise) | EVE | On Loan | 01/07/2023 | Joined Juventus on a two-year loan deal | 31/08/2021 |
 Mina (Yerry) | EVE | Doubt 75% | 12/12/2021 | Calf injury Picked up a calf injury against Arsenal on 6/12. [Source] | 06/12/2021 |
 João Virgínia | EVE | On Loan | 01/07/2022 | Joined Sporting Lisbon on a season-long loan [Source] | 25/08/2021 |
| Rodríguez (James) | EVE | Unavailable | Unknown | Transferred to Al Rayyan [Source] | 22/09/2021 |
| Rondón (Salomón) | EVE | Doubt 50% | 12/12/2021 | Hamstring injury Substituted with a hamstring injury on 1/12 and will be assessed by the club's physios. "Feeling better" as of 3/12 but still awaiting the results of a scan and didn't feature against Arsenal on 6/12. [Source] | 06/12/2021 |
 Sigurdsson (Gylfi) | EVE | Unavailable | Unknown | Not included in Everton's 25-man Premier League squad | 07/10/2021 |
 Bamford (Patrick) | LEE | Doubt 25% | 18/12/2021 | Muscle injury Media reports suggest he injured himself in the Brentford game on 5/12. [Source] | 08/12/2021 |
| Kiko Casilla | LEE | On Loan | 01/07/2022 | Joined Elche CF on a season-long loan [Source] | 13/07/2021 |
| Cooper (Liam) | LEE | Doubt 25% | Unknown | Hamstring injury Substituted in the match against Brentford on 5/12 but his manager does not know the extent of the problem. Media reports suggest he will be missing for a while. [Source] | 08/12/2021 |
| Hélder Costa | LEE | On Loan | 01/07/2022 | Joined Valencia on a season-long loan [Source] | 01/09/2021 |
| Koch (Robin) | LEE | Injured | Unknown | Pelvic Missed the Everton game on 21/8 after complaining of pain in his pubis and has been missing since. Underwent surgery in the United States on 14/10. Still unavailable as of 25/11 but in the final stages of his recovery. [Source] | 25/11/2021 |
| Phillips (Kalvin) | LEE | Doubt 25% | 08/02/2022 | Hamstring injury Substituted in the match against Brentford on 5/12 with a hamstring injury. Media reports suggest he could be out for two months. [Source] | 08/12/2021 |
| Poveda-Ocampo (Ian Carlo) | LEE | On Loan | 01/07/2022 | Joined Blackburn Rovers on a season-long loan [Source] | 23/08/2021 |
| Struijk (Pascal) | LEE | Doubt 75% | 11/12/2021 | Knock Took a knock to his hip in the match against Crystal Palace on 30/11. Was expected to face Brentford on 5/12 but "still finishing up" his recovery. [Source] | 05/12/2021 |
 Ricardo Pereira | LEI | Injured | Unknown | Hamstring injury Felt tightness in his hamstring ahead of the Chelsea game on 20/11 and missed out. Ruled out for "a few weeks" on 24/11. [Source] | 04/12/2021 |
| Fofana (Wesley) | LEI | Injured | 01/01/2022 | Leg injury Suffered a broken leg and ligament damage in the pre-season game against Villarreal on 4/8 and faced a lengthy spell on the sidelines. A January return was mooted but the player is recovering so well that he might be back sooner. [Source] | 18/11/2021 |
 Justin (James) | LEI | Doubt 50% | 12/12/2021 | Lack of match fitness Recovered from an ACL injury sustained on 10/2 but will get game-time with the under-23s before being considered for a first-team return. It was reported on 29/11 that he had suffered a minor setback but he has since returned to full training. The match against Aston Villa on 5/12 may come too soon. [Source] | 05/12/2021 |
 Mendy (Nampalys) | LEI | Unavailable | Unknown | Not included in Leicester's 25-man Premier League squad | 07/10/2021 |
 Praet (Dennis) | LEI | On Loan | 01/07/2022 | Joined Torino on a season-long loan [Source] | 31/08/2021 |
 Schmeichel (Kasper) | LEI | Doubt 75% | 12/12/2021 | Hand injury Picked up a thumb injury against Aston Villa on 5/12 and is set for an X-ray. [Source] | 05/12/2021 |
 Firmino | LIV | Injured | 11/12/2021 | Hamstring injury Substituted with a hamstring injury against Atletico Madrid on 3/11. Ruled out for "more than four" weeks. His manager said on 30/11 that he needed "another week to do more football stuff" in training before being considered for a return. [Source] | 30/11/2021 |
| Davies (Ben) | LIV | On Loan | 01/07/2022 | Joined Sheffield United on a season-long loan [Source] | 17/08/2021 |
 Elliott (Harvey) | LIV | Injured | Unknown | Ankle injury Sustained a serious ankle injury in the match against Leeds on 12/9 and will undergo surgery. [Source] | 12/09/2021 |
 Jones (Curtis) | LIV | Injured | Unknown | Eye Injury Missed the Champions League tie against Atletico Madrid on 3/11 after "sustaining a knock to his eye in training". Has been sidelined since and was again ruled out for "a number of weeks" on 16/11. Still waiting for the green light from the medical team as of 30/11. [Source] | 30/11/2021 |
 Shaqiri (Xherdan) | LIV | Unavailable | Unknown | Transferred to Lyon | 23/08/2021 |
| Rhys Williams | LIV | On Loan | 01/07/2022 | Joined Swansea City on a season-long loan [Source] | 31/08/2021 |
 Woodburn (Ben) | LIV | On Loan | 01/07/2022 | Joined Hearts on a season-long loan | 23/08/2021 |
 Aké (Nathan) | MCI | Doubt 75% | 11/12/2021 | Back injury Substituted with back pain in the match against Leipzig on 7/12. [Source] | 07/12/2021 |
 Jesus | MCI | Doubt 75% | 11/12/2021 | Knock Will miss Man City's Champions League match against Leipzig on 7/12 with a knock. [Source] | 06/12/2021 |
| Doyle (Tommy) | MCI | On Loan | 01/07/2022 | Joined Hamburger on a season-long loan [Source] | 31/08/2021 |
 Foden (Phil) | MCI | Doubt 75% | 11/12/2021 | Ankle injury Substituted as a "precaution" because of recurrent ankle pain in the match against Leipzig on 11/12. [Source] | 07/12/2021 |
 Mendy (Benjamin) | MCI | Unavailable | Unknown | Suspended by club | 01/09/2021 |
| Torres (Ferran) | MCI | Injured | 01/01/2022 | Foot injury Suffered a foot fracture while on international duty with Spain. Ruled out for two-to-three months on 15/10. [Source] | 15/10/2021 |
| Cavani (Edinson) | MUN | Injured | 18/12/2021 | Tendon Injury Missed the Manchester derby on 6/11 with a reported tendon injury. Not included in Uruguay's squad for the November internationals for medical reasons and hasn't featured for his club after that. Expected back in full training on 13/12. [Source] | 07/12/2021 |
 Martial (Anthony) | MUN | Doubt 75% | 11/12/2021 | Knee injury Missed the match against Crystal Palace on 5/12 after "feeling pain" in training. [Source] | 08/12/2021 |
 Pogba (Paul) | MUN | Injured | Unknown | Thigh injury Picked up a thigh injury while on duty with France over the November international break. Will be out for some time but no exact timeframe has been put on his recovery. [Source] | 19/11/2021 |
| Varane (Raphael) | MUN | Injured | 18/12/2021 | Hamstring injury Substituted after complaining of hamstring discomfort in the match against Atalanta on 2/11. Ruled out for a month on 3/11. Out on the grass as of 1/12 but not ready for a playing return. Expected back in full training on 13/12. [Source] | 07/12/2021 |
 Wan-Bissaka (Aaron) | MUN | Doubt 75% | 11/12/2021 | Knee injury Picked up knocks on his wrist and knee in the match against Young Boys on 8/12 and the latter required him to be taken off on a stretcher. [Source] | 08/12/2021 |
| Anderson (Elliot) | NEW | Doubt 25% | Unknown | Knock Picked up an injury playing for the under-23s on 26/11. [Source] | 01/12/2021 |
 Dummett (Paul) | NEW | Injured | Unknown | Calf injury Returned to full training as of 24/8 after recovering from a calf problem that forced him to miss the first two games of 2021/22. His then manager confirmed on 16/9 that he had suffered a recurrence of the same calf problem. Still sidelined as of 19/11. [Source] | 19/11/2021 |
 Fraser (Ryan) | NEW | Doubt 75% | 12/12/2021 | Hamstring injury Missed the match against Burnley on 4/12 with a minor hamstring injury. [Source] | 04/12/2021 |
 Longstaff (Matthew) | NEW | On Loan | Unknown | Joined Aberdeen on a season-long loan [Source] | 28/08/2021 |
| Mathias Normann | NOR | Doubt 50% | 11/12/2021 | Pelvic Taken with a recurrence of a pelvic injury in the match against Wolves on 27/11. Has been sidelined since but has had injections in the affected area and could be back for the Manchester United game on 11/12. [Source] | 04/12/2021 |
 Byram (Sam) | NOR | Injured | Unknown | Lack of match fitness Back in training as of October after 20 months out with a hamstring problem but not yet being considered for first-team selection. Featured for the under-23s on 19/11 and on 29/11. [Source] | 03/12/2021 |
 Hernández (Onel) | NOR | On Loan | 01/07/2022 | Joined Middlesbrough on a season-long loan [Source] | 30/08/2021 |
 Hugill (Jordan) | NOR | On Loan | 01/07/2022 | Joined West Bromwich Albion on a season-long loan [Source] | 25/08/2021 |
| Rashica (Milot) | NOR | Injured | 01/01/2022 | Groin Injury Missed the match against Newcastle on 30/11 with a groin problem. Ruled out for three to four weeks. [Source] | 03/12/2021 |
 Stiepermann (Marco) | NOR | Unavailable | Unknown | Left the club by mutual consent on 30/6. [Source] | 01/07/2021 |
 Williams (Brandon) | NOR | Unavailable | 14/12/2021 | Ineligible to face his parent club on 11/12. | 04/12/2021 |
 Zimmermann (Christoph) | NOR | Injured | Unknown | Ankle injury Ruled out of the Arsenal game on 11/9 with an ankle problem and has been unavailable since. Will undergo surgery on 25/10 and be out of training for around six weeks. [Source] | 04/12/2021 |
 Armstrong (Stuart) | SOU | Injured | Unknown | Calf injury Missed the Norwich game on 20/11 with a calf problem and has been sidelined since. Still missing for the Brighton game on 4/12. [Source] | 03/12/2021 |
 Bednarek (Jan) | SOU | Injured | Unknown | Calf injury Substituted with a calf problem against Leicester on 1/12. His manager said afterwards that the withdrawal was hopefully just precautionary but he was subsequently ruled out of the Brighton game on 4/12. [Source] | 03/12/2021 |
 Forster (Fraser) | SOU | Doubt 25% | 12/12/2021 | Hamstring injury Picked up a "little bit of an injury" in training before the Brighton game on 4/12 and missed out. [Source] | 04/12/2021 |
 McCarthy (Alex) | SOU | Doubt 25% | 12/12/2021 | Hamstring injury Suffered a suspected hamstring injury in the match against Brighton on 4/12. Could be out for "a long time". [Source] | 04/12/2021 |
| N'Lundulu (Daniel) | SOU | On Loan | 01/07/2022 | Joined Lincoln City on a season-long loan [Source] | 14/07/2021 |
 Obafemi (Michael) | SOU | Unavailable | Unknown | Transferred to Swansea City [Source] | 31/08/2021 |
 Romeu (Oriol) | SOU | Suspended | 15/12/2021 | 1 Match Ban Suspended for one match after picking up his fifth booking of the season on 4/12. | 04/12/2021 |
| Salisu (Mohammed) | SOU | Suspended | 15/12/2021 | 1 Match Ban Suspended for one match after picking up his fifth booking of the season on 4/12. | 04/12/2021 |
 Alderweireld (Toby) | TOT | Unavailable | Unknown | Transferred to Al-Duhail SC [Source] | 27/07/2021 |
 Aurier (Serge) | TOT | Unavailable | Unknown | Left the club by mutual consent [Source] | 31/08/2021 |
| Gil (Bryan) | TOT | Doubt 75% | 12/12/2021 | Illness Missed the match against Norwich on 5/12 because of illness. [Source] | 06/12/2021 |
 Lamela (Erik) | TOT | Unavailable | Unknown | Transferred to Sevilla | 27/07/2021 |
| Emerson Royal | TOT | Doubt 75% | 12/12/2021 | Illness Missed the match against Norwich on 5/12 because of illness. [Source] | 06/12/2021 |
 Lo Celso (Giovani) | TOT | Doubt 50% | 12/12/2021 | Knock Returned from international duty with Argentina in November with what his club manager said was a "little problem" and hasn't been able to feature since. Expected to return to training after the Norwich game on 5/12. [Source] | 05/12/2021 |
| Reguilón (Sergio) | TOT | Doubt 75% | 12/12/2021 | Muscle injury Substituted in the match against Norwich on 5/12 but neither player nor manager thinks the issue is serious. [Source] | 05/12/2021 |
| Romero (Cristian) | TOT | Injured | Unknown | Hamstring injury Suffered a hamstring injury in Argentina's match against Brazil on 16/11 and is set for a long spell on the sidelines. [Source] | 03/12/2021 |
| Baah (Kwadwo) | WAT | Injured | Unknown | Ankle injury It was reported on 5/11 that he had fractured his ankle and will be sidelined for "some weeks". Has undergone surgery and is beginning his rehab as of 18/11. [Source] | 18/11/2021 |
 Chalobah (Nathaniel) | WAT | Unavailable | Unknown | Transferred to Fulham [Source] | 01/09/2021 |
 Deeney (Troy) | WAT | Unavailable | Unknown | Transferred to Birmingham City [Source] | 31/08/2021 |
 Tom Dele-Bashiru | WAT | On Loan | 01/07/2022 | Joined Reading on a season-long loan [Source] | 13/08/2021 |
| Etebo (Peter) | WAT | Injured | 26/02/2022 | Thigh injury Ruled out for four to five months after tearing a quad muscle in the match against Newcastle on 25/9. Doing gym work as of 18/11. [Source] | 18/11/2021 |
 Foster (Ben) | WAT | Injured | 15/01/2022 | Groin Injury Missed the Leicester game on 28/11 with a groin strain. Subsequently ruled out until January after a scan. [Source] | 30/11/2021 |
 Gray (Andre) | WAT | On Loan | 01/07/2022 | Joined QPR on a season-long loan [Source] | 31/08/2021 |
 Hungbo (Joseph) | WAT | On Loan | 01/07/2022 | Joined Ross County on a season-long loan [Source] | 18/08/2021 |
 Masina (Adam) | WAT | Injured | Unknown | Thigh injury Substituted with a muscle injury in the match against Chelsea on 4/12. His manager thinks he may be out for an extended period as a result. [Source] | 02/12/2021 |
| N'Koulou (Nicolas) | WAT | Injured | 15/01/2022 | Hamstring injury Substituted with a knee injury against Manchester United on 20/11 and has been missing since. Ruled out until the New Year on 30/11. [Source] | 30/11/2021 |
 Navarro (Marc) | WAT | Unavailable | Unknown | Left the club by mutual consent [Source] | 31/08/2021 |
| Perica (Stipe) | WAT | Unavailable | Unknown | Transferred to Maccabi Tel Aviv [Source] | 14/08/2021 |
| Pollock (Matthew) | WAT | On Loan | 01/07/2022 | Joined Cheltenham Town on a season-long loan [Source] | 30/08/2021 |
 Quina (Domingos) | WAT | On Loan | 01/07/2022 | Joined Fulham on a season-long loan [Source] | 01/09/2021 |
 Ismaila Sarr | WAT | Injured | Unknown | Knee injury Substituted with a knee ligament injury against Manchester United on 20/11 and set for a spell on the sidelines. An update on 30/11 said that he would have a further scan in a month's time. [Source] | 30/11/2021 |
 Sema (Ken) | WAT | Injured | 10/12/2021 | Knee injury It was reported on 5/11 that he had picked up an MCL injury to his knee and will be sidelined for "some weeks". Running outside as of 26/11 and aiming to rejoin full training the week after. [Source] | 30/11/2021 |
| Sierralta (Francisco) | WAT | Injured | Unknown | Hamstring injury Ruled out of the Manchester United match on 20/11 after sustaining a hamstring injury while on international duty with Chile. Has been sidelined sicne. Running outside as of 30/11. [Source] | 30/11/2021 |
 Isaac Success | WAT | Unavailable | Unknown | Transferred to Udinese [Source] | 26/08/2021 |
| Zinckernagel (Philip) | WAT | On Loan | 01/07/2022 | Joined Nottingham Forest on a season-long loan [Source] | 08/08/2021 |
| Alves (Frederik) | WHU | On Loan | 01/07/2022 | Joined Sunderland on a season-long loan [Source] | 14/08/2021 |
| Coventry (Conor) | WHU | On Loan | 01/07/2022 | Joined Peterborough United on a season-long loan [Source] | 31/08/2021 |
 Cresswell (Aaron) | WHU | Doubt 75% | 12/12/2021 | Back injury Suffered pain in his back after colliding with the post in the match against Man City on 28/11. Missed the Brighton game on 1/12. Had done some "light training" ahead of the Chelsea match on 4/12 but wasn't involved. [Source] | 04/12/2021 |
 Johnson (Ben) | WHU | Doubt 25% | Unknown | Hamstring injury Substituted with a hamstring injury in the match against Chelsea on 4/12. [Source] | 07/12/2021 |
 Ogbonna (Angelo) | WHU | Injured | Unknown | Knee injury Taken off against Liverpool on 7/11 after needing stitches to an eye wound but his manager also revealed after full-time that he had taken a knock. A scan later revealed that he had suffered an ACL injury and that he would be out or a lengthy period of time. [Source] | 09/11/2021 |
 Reid (Winston) | WHU | Unavailable | Unknown | Left the club by mutual consent [Source] | 22/09/2021 |
 Zouma (Kurt) | WHU | Doubt 25% | Unknown | Hamstring injury Limped off in the match against Chelsea on 4/12. [Source] | 07/12/2021 |
| Ait Nouri (Rayan) | WOL | Doubt 75% | 11/12/2021 | Knock Picked up an injury in the match against Liverpool on 4/12 but his manager doesn't yet know the extent of it. [Source] | 04/12/2021 |
 Boly (Willy) | WOL | Injured | Unknown | Muscle injury Ruled out for an as yet undetermined period of time with a muscular problem on 26/11. May not return until 2022. [Source] | 30/11/2021 |
 Jonny | WOL | Injured | 01/01/2022 | Knee injury Ruled out for the rest of the season with an anterior cruciate ligament injury on 5/4. Will undergo surgery in the week commencing 12/4. An update on 30/9 said he was on course for "a return in the new year". [Source] | 30/09/2021 |
 Rui Patrício | WOL | Unavailable | Unknown | Transferred to Roma | 14/07/2021 |
 Gibbs-White (Morgan) | WOL | On Loan | 01/07/2022 | Joined Sheffield United on a season-long loan [Source] | 31/08/2021 |
| Marçal | WOL | Doubt 75% | 11/12/2021 | Illness Missed the matches against Burnley on 1/11 and Liverpool on 4/12 after a positive Covid-19 test. Expected back against Man City on 11/12. [Source] | 04/12/2021 |
| Mosquera (Yerson) | WOL | Injured | 26/02/2022 | Hamstring injury Suffered a "high-grade" hamstring injury against Spurs on 22/9. Ruled out for around four to five months on 30/9. [Source] | 30/09/2021 |
 Neto (Pedro) | WOL | Injured | 04/12/2021 | Knee injury Taken off with a significant knee injury against Fulham on 9/4. Underwent surgery and has been unavailable since. A December playing return was suggested by his manager on 24/8. Will undergo a specialist review in October but no further timeframe has been suggested. [Source] | 30/09/2021 |
| Söndergaard (Andreas) | WOL | On Loan | 15/01/2022 | Joined Randers on loan until the end of 2021 [Source] | 31/08/2021 |