Chelsea’s key Fantasy assets all start against Bournemouth with Christian Pulisic (£7.4m) joining Tammy Abraham (£8.0m) in the front-three.
Meanwhile, Mason Mount (£6.6m) is also in the starting line-up but may well be sat in a central midfield trio alongside N’Golo Kanté (£5.0m) and Jorginho (£5.0m).
However, those who made a move for the differential Reece James (£5.0m) were left disappointed as he was named on the bench.
The exciting right-back has started four of the last five but is among the substitutes against Bournemouth.
The Cherries have gone with something relatively experimental in light of recent injuries.
Eddie Howe has opted for a 4-4-2 diamond system featuring Josh King (£6.1m) and Ryan Fraser (£6.9m) as the central strikers.
That sees Cesar Azpilicueta (£5.8m) return to the right of defence with Emerson Palmieri (£5.5m) starts on the left.
Meanwhile, Leicester have kept the exact same line-up rolled out in the 4-1 win at Aston Villa, hinting that Brendan Rodgers may continue using it after Gameweek 16.
The Foxes once again are laid out in a 4-3-1-2 system, with Dennis Praet (£5.3m) and Youri Tielemans (£6.6m) either side of Wilfred Ndidi (£5.0m) and James Maddison (£7.8m) behind Jamie Vardy (£10.1m) and Kelechi Iheancho (£5.7m).
Opponents Norwich include Todd Cantwell (£4.7m) in their starting line-up after he was benched in Gameweek 16.
Sheffield United name an unchanged side to face Aston Villa, Dean Smith hands rare starts to Kortney Hause (£4.4m) and Henri Lansbury (£4.4m).
After coming back into the team for the 5-0 defeat at Spurs, Matt Lowton (£4.4m) returns to the bench for Burnley.
Phil Bardsley (£4.3m) reclaims his right-back berth after an injury, while Ashley Barnes (£6.3m) and Ashley Westwood (£5.4m) return after missing out on Gameweek 16.
Chris Wood (£6.2m) has also shaken off the knock Sean Dyche revealed on Thursday to start up-front in the 4-4-2 system.
In light of recent injuries to Allan Saint-Maximin (£5.4m) and Jonjo Shelvey (£5.1m), Steve Bruce is somewhat limited in the team he can name at Turf Moor.
He has stuck with a five-man defence but looks to be deploying three central midfielders behind a front-pairing of Andy Carroll (£5.4m) and Joelinton (£5.6m), rather than sticking with a 5-4-1 formation.
Burnley XI: Pope; Pieters, Mee, Tarkowski, Bardsley; McNeil, Westwood, Cork, Hendrick; A Barnes, Wood.
Newcastle United XI: Dúbravka; Willems, Dummett, Schär, Fernández, Manquillo; Atsu, S Longstaff, Hayden; Joelinton, Carroll.
Chelsea XI: Kepa; Emerson, Rüdiger, Zouma, Azpilicueta; Mount, Kanté, Jorginho; Pulisic, Abraham, Willian.
Bournemouth XI: Ramsdale; Rico, Mepham, Francis, Stacey; Lerma; Gosling, Billing; L Cook; J King, Fraser.
Leicester City XI: Schmeichel; Chilwell, Söyüncü, Evans, R Pereira; Tielemans, Ndidi, Praet; Maddison; Iheanacho, Vardy.
Norwich City XI: Krul; Aarons, Zimmermann, Godfrey, Byram; Tettey, Trybull; Buendía, McLean, Cantwell; Pukki.
Sheffield Utd XI: Henderson; Basham, Egan, O’Connell; Baldock, Lundstram, Norwood, Fleck, Stevens; Mousset, McGoldrick.
Aston Villa XI: Heaton; Guilbert, Engels, Hause, Targett; McGinn, Nakamba, Lansbury; El Ghazi, Wesley, Grealish.
