Following the postponement of Brentford v Manchester United, Gameweek 17 now gets underway with Norwich City v Aston Villa at 19.45 GMT, followed by Manchester City v Leeds United 15 minutes later.
Gianni and Seb will be following the action in the embedded video below and over on our YouTube channel.
At Carrow Road, Dean Smith makes four changes from Gameweek 16, with Ben Gibson, Brandon Williams, Jacob Sorensen and Todd Cantwell coming in for Grant Hanley, Dimitris Giannoulis, Lukas Rupp and Josh Sargent.
Steven Gerrard, meanwhile, makes just the one change, with Emiliano Buendia replacing the injured Marvelous Nakamba, who may miss the rest of the 2021/22 season after suffering a knee injury against Liverpool at the weekend.
As a result, Ollie Watkins leads the line once again, with Danny Ings having to settle for a place on the bench.
Notably, Jed Steer, Morgan Sanson, Anwar El Ghazi and Keinan Davis are all absent from the matchday squad, with Gerrard revealing in his pre-match press conference that two first-team players had tested positive for Covid-19.
Meanwhile, Pep Guardiola makes four changes, as John Stones comes in at full-back for the suspended Joao Cancelo, while further forward, Kevin De Bruyne, Riyad Mahrez and Phil Foden are in for Ilkay Gundogan, Raheem Sterling and Gabriel Jesus, all of whom drop to the bench.
Kyle Walker surprisingly misses out, with reports suggesting he is short of full fitness.
For Leeds, they name an unchanged XI, as Liam Cooper, Kalvin Phillips and Patrick Bamford remain out.
GAMEWEEK 17 LINE-UPS
Norwich City XI: Krul, Aarons, Kabak, Gibson, Williams, Sorensen, Gilmour, McLean, Placheta, Cantwell, Pukki
Subs: Gunn, Byram, Tomkinson, Mumba, Giannoulis, Rowe, Idah, Dowell, Dickson-Peters
Aston Villa XI: Martinez, Cash, Konsa, Mings, Targett, Luiz, McGinn, Ramsey, Buendia, Young, Watkins
Subs: Marschall, Tuanzebe, Hause, Iroegbunam, Chukwuemeka, Philogene-Bidace, Trezeguet, Archer, Ings
Manchester City XI: Ederson, Stones, Dias, Laporte, Zinchenko, Rodri, De Bruyne, Bernardo, Mahrez, Foden, Grealish
Subs: Steffen, Ake, Sterling, Gundogan, Jesus, Fernandinho, Egan-Riley, Palmer, Wilson-Esbrand
Leeds United XI: Meslier, Shackleton, Ayling, Llorente, Firpo, Forshaw, Dallas, Raphinha, Roberts, Harrison, James
Subs: Klaesson, Gelhardt, Cresswell, Drameh, Summerville, Greenwood, Klich, McCarron, Jenkins
