Pierre-Emerick Aubameyang (£11.5m) and Alexandre Lacazette (£9.6m) both start for Arsenal as they host Burnley in Gameweek 18’s Saturday lunch-time kick-off.
Sead Kolasinac (£5.0m) returns to the starting line-up after being a fitness doubt for the game, while Ainsley Maitland-Niles (£4.4m) is the one to replace the injured Hector Bellerín (£5.4m) at right-back.
Meanwhile, Mohamed Elneny (£4.3m) comes into the side so that Lucas Torreira (£5.2m) can get a rest on the bench.
Aubameyang and Lacazette are joined in attack by Mesut Özil (£8.0m).
Burnley have lined up with a 5-3-2 formation and are expected to try to stay compact and hit Arsenal on the break.
James Tarkowski (£4.7m), Ben Mee (£4.7m) and Kevin Long (£4.2m) are the centre-backs with Charlie Taylor (£4.4m) and Phil Bardsley (£4.2m) flanking them.
Sean Dyche has typically used just one forward this season but he has bolstered the attack today with the inclusion of Ashley Barnes (£5.6m) and Chris Wood (£6.2m) up front.
Arsenal XI: Leno, Maitland-Niles, Sokratis, Monreal, Kolasinac, Xhaka, Elneny, Guendouzi, Ozil, Lacazette, Aubameyang.
Burnley XI: Hart, Bardsley, Tarkowski, Mee, Long, Taylor, Cork, Westwood, Hendrick, Barnes, Wood.
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