Four Premier League matches kick off at 3pm BST today, including reigning champions Manchester City against newly promoted Norwich City.
Aston Villa v Newcastle United, Crystal Palace v Brentford and Leeds United v Everton are the other top-flight fixtures taking place at the traditional Saturday afternoon start time.
The headline team news comes from the Etihad as Pep Guardiola makes five changes to the side that lost 1-0 to Tottenham Hotspur.
Aymeric Laporte, Kyle Walker, Rodri, Gabriel Jesus and Bernardo Silva are all recalled to the starting XI, with Raheem Sterling, Riyad Mahrez, Nathan Ake, Benjamin Mendy and Fernandinho dropping to the bench.
An ankle injury keeps Kevin De Bruyne out, while John Stones isn’t part of the hosts’ matchday squad.
Norwich are unchanged from the side that lost 3-0 at home to Liverpool last Saturday.
That’s also the case with Brentford, as Bryan Mbeumo gets set for another out-of-position run-out alongside Ivan Toney.
Summer signings Conor Gallagher and Joachim Andersen get their first Palace starts, with Christian Benteke also recalled. Jordan Ayew, Jairo Riedewald and Jean-Philippe Mateta drop to the bench.
Aston Villa boss Dean Smith makes two changes to the team that lost to newly promoted Watford last weekend, with Jacob Ramsey and Douglas Luiz replacing Matt Targett and Marvelous Nakamba.
Targett’s benching means that Ashley Young starts at left-back.
Joe Willock starts for Newcastle as Steve Bruce makes three changes to the Magpies side that lost at home to West Ham last Sunday.
Willock replaces the injured Jonjo Shelvey in midfield, with Fabian Schar and captain Jamaal Lascelles coming into defence in place of Emil Krafth and Ciaran Clark.
Kalvin Phillips and Junior Firpo are make the Leeds line-up after fitness-related benchings in Gameweek 1, with Robin Koch and Rodrigo dropping to the bench.
Yerry Mina for Mason Holgate and Alex Iwobi for Andros Townsend are Everton’s two alterations.
GAMEWEEK 2 LINE-UPS
Aston Villa XI: Martinez, Cash, Konsa, Mings, Young, McGinn, Ramsey, Douglas Luiz, El Ghazi, Buendia, Ings
Subs:Â Steer, Targett, Wesley, Hourihane, Tuanzebe, Nakamba, Hause, Philogene-Bidace, Chukwuemeka
Newcastle XI: Woodman, Murphy, Schar, Fernandez, Lascelles, Ritchie, Hayden, Willock, Almiron, Wilson, Saint-Maximin
Subs:Â Gillespie, Clark, Joelinton, Lewis, Hendrick, Krafth, Fraser, Gayle, S. Longstaff
Crystal Palace XI: Guaita, Ward, Andersen, Guehi, Mitchell, Kouyate, Schlupp, McArthur, Benteke, Gallagher, Zaha.
Subs:Â Butland, Matthews, Tomkins, Ayew, Mateta, Kelly, Riedewald, Rak-Sakyi.
Brentford XI: Raya, Ajer, Jansson, Pinnock, Henry, Janelt, Onyeka, Mbeumo, Norgaard, Canos, Toney.
Subs:Â Goode, Forss, Wissa, Fernandez, Ghoddos, Dervisoglu, Bidstrup, Sorensen, Roerslev.
Leeds: Meslier, Ayling, Struijk, Cooper, Firpo, Phillips, Raphinha, Dallas, Klich, Harrison, Bamford.
Subs:Â Forshaw, Roberts, Klaesson, Helder Costa, Rodrigo, Summerville, Shackleton, Cresswell, Drameh.
Everton: Pickford, Coleman, Mina, Keane, Digne, Allan, Doucoure, Gray, Richarlison, Iwobi, Calvert-Lewin.
Subs:Â Kenny, Holgate, Delph, Townsend, Begovic, Gbamin, Davies, Kean, Branthwaite.
Manchester City XI: Ederson, Cancelo, Dias, Laporte, Walker, Gundogan, Rodri, Grealish, Silva, Torres, Jesus.
Subs:Â Steffen, Ake, Zinchenko, Mendy, Fernandinho, Sterling, Mahrez, Doyle, Palmer.
Norwich City XI: Krul, Aarons, Hanley, Gibson, Giannoulis, Lees-Melou, Gilmour, Rupp, Cantwell, Pukki, Rashica.
Subs:Â Gunn, Omobamidele, Dowell, Tzolis, Sorensen, McLean, Sargent, Mumba, Idah.
FANTASY5
There’s still time to enter today’s Fantasy5 contest, in which you can win £10,000 without paying a penny.
Simply pick five players from the nominated Gameweek 2 matches and, if they all exceed their Fantasy ‘points targets’ (a par score set by Fantasy5 for each asset), you’ll be in the money.
The deadline is at 3pm BST – so get those entries in now.
We’ve selected our own picks for Gameweek 2 in the article below, with Ted Talks FPL following suit.
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