The second and final Premier League match of the day is a big one, as Chelsea host Tottenham Hotspur in a London derby.
Kick-off at Stamford Bridge is 16:30 BST.
Thomas Tuchel makes two changes for Chelsea, with Marc Cucurella and Ruben Loftus-Cheek coming in for Ben Chilwell and Cesar Azpilicueta, both of whom are substitutes.
That suggests Reece James will feature as a right-sided centre-back alongside Thiago Silva and Kalidou Koulibaly.
Mateo Kovacic, meanwhile, misses out because of a knee injury, while Marcos Alonso is absent as he finalises his transfer to Barcelona.
As for Spurs, they are unchanged from Gameweek 1, with Matt Doherty and Ivan Perisic on the bench with new signing Richarlison.
However, they are without the injured Clement Lenglet and Oliver Skipp.
GAMEWEEK 2 LINE-UPS
Chelsea XI: Mendy, James, Silva, Koulibaly, Loftus-Cheek, Kante, Jorginho, Cucurella, Havertz, Mount, Sterling
Subs: Kepa, Pulisic, Chalobah, Broja, Hudson-Odoi, Chilwell, Ziyech, Gallagher, Azpilicueta
Tottenham Hotspur XI: Lloris, Romero, Dier, Davies, Royal, Bentancur, Hojbjerg, Sessegnon, Kulusevski, Son, Kane
Subs: Forster, Doherty, Sanchez, Richarlison, Gil, Perisic, Tanganga, Moura, Bissouma
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