Four more Double Gameweek 34 matches get underway at 2pm BST on Sunday, including Fulham v Manchester City.
The visitors are without Kevin De Bruyne, who is “not fully fit” according to reporter Mike Minay. Riyad Mahrez and Julian Alvarez come into the starting XI, with Bernardo Silva dropping to the bench.
Fulham also make two changes as Bobby De Cordova-Reid and Carlos Vinicius replace Manor Solomon and Daniel James.
Elsewhere, the headline team news from St James’ Park is that Alexander Isak starts for Newcastle United. He comes in for Callum Wilson, with Dan Burn, Jacob Murphy and Anthony Gordon the other returnees.
James Ward-Prowse is fit enough to start for their opponents, Southampton. The alterations – and there are five in total – see Armel Bella-Kotchap, Lyanco, Stuart Armstrong, Moussa Djenepo and Kamaldeen Sulemana feature.
At Old Trafford, Tyrell Malacia and Marcel Sabitzer replace Aaron Wan-Bissaka and Antony, both of whom drop to the bench, while Aston Villa are unchanged for the fourth successive game.
On the south coast, Gary O’Neil makes two changes to his Bournemouth XI. The injured Marcus Tavernier and Chris Mepham drop out as Adam Smith and Dango Ouattara come in.
Leeds United, meanwhile, bring in Rasmus Kristensen, Crysencio Summerville and Wilfried Gnonto for Junior Firpo, Rodrigo and the injured Luis Sinisterra, in what looks like a 3-4-3 formation.
GAMEWEEK 34 LINE-UPS
Bournemouth XI: Neto, Smith, Senesi, Kelly, Vina, Rothwell, Lerma, Christie, Billing, Ouattara, Solanke
Subs: Travers, Stephens, Cook, Brooks, Stacey, Moore, Semenyo, Zabarnyi, Anthony
Leeds United XI: Meslier, Kristensen, Koch, Cooper, Ayling, Roca, McKennie, Harrison, Gnonto, Summerville, Bamford
Subs: Robles, Firpo, Forshaw, Aaronson, Rodrigo, Struijk, Rutter, Wober, Greenwood
Fulham XI: Leno, Tete, Tosin, Ream, Robinson, Reed, Palhinha, Wilson, Pereira, De Cordova-Reid, Vinicius
Subs: Rodak, Duffy, Cedric, Diop, Kebano, Cairney, Lukic, Solomon, James
Manchester City XI: Ederson, Walker, Stones, Dias, Akanji, Rodri, Gundogan, Mahrez, Grealish, Alvarez, Haaland
Subs: Carson, Ortega, Laporte, Lewis, Phillips, Gomez, Foden, Bernardo, Perrone
Manchester United XI: De Gea, Dalot, Lindelof, Shaw, Malacia, Casemiro, Eriksen, Fernandes, Sabitzer, Sancho, Rashford
Subs: Butland, Maguire, Martial, Fred, Antony, Weghorst, Pellistri, Wan-Bissaka, Williams
Aston Villa XI: Martinez, Young, Konsa, Mings, Moreno, McGinn, Dendoncker, Douglas Luiz, Ramsey, Buendia, Watkins
Subs: Olsen, Carlos, Traore, Chambers, Duran, Digne, Revan, O’Reilly, K Young
Newcastle United XI: Pope, Trippier, Schar, Botman, Burn, Guimaraes, Willock, Joelinton, Murphy, Gordon, Isak
Subs: Dubravka, Dummett, Wilson, Ritchie, Lewis, Targett, Manquillo, Almiron, Anderson
Southampton XI: McCarthy, Walker-Peters, Bednarek, Bella-Kotchap, Lyanco, S Armstrong, Ward-Prowse, Lavia, Sulemana, Djenepo, Alcaraz
Subs: Maitland-Niles, Caleta-Car, A Armstrong, Adams, Mara, Elyounoussi, Diallo, Bazunu, Walcott
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