Eden Hazard (£10.5m) and Mateo Kovacic (£6.0m) make their first starts of the season as Chelsea attempt to win on Tyneside for the first time in the league since 2011/12.
Willian (£7.5m) and Ross Barkley (£6.0m), as would perhaps be expected, are the two men to make way as Maurizio Sarri otherwise rolls out the same team that beat Arsenal last weekend.
Marcos Alonso (£6.6m), who comes into this match on the back of successive double-digit hauls, is now the second-most popular defender in Fantasy Premier League after being bought by 470,266 new managers ahead of Gameweek 3.
Chelsea assets are popular in the Fantasy community after their 100% start to the season: five of their front six (the exception being Kovacic) have been bought by more than 100,000 FPL bosses since the Gameweek 2 deadline passed.
It’s all change in the Newcastle United starting XI, with six alterations to the team that drew 0-0 with Cardiff City. The injured Jamaal Lascelles (£5.0m) and Jonjo Shelvey (£5.5m) are among the players to drop out, while there are starts for new signings Fabian Schar (£4.9m), Federico Fernandez (£4.5m), Ki Sung-yeung (£4.9m) and Salomon Rondon (£5.9m).
Rafael Benitez seems to be rolling out a five-man defence, too, switching from his regular 4-4-1-1 system.
Slavisa Jokanovic has also rung the changes at Craven Cottage, with Ryan Sessegnon (£6.4m) and Fabri (£4.5m) among five players to drop to the bench. Denis Odoi (£4.5m) returns from suspension, while Marcus Bettinelli (£4.5m) is a surprise inclusion between the sticks. Andre Schurrle (£5.9m) also returns.
The Burnley team news is much more straightforward: Sean Dyche has named an unchanged starting XI for the third league match in a row.
Chelsea XI (4-3-3): Kepa; Azpilicueta, Rudiger, Luiz, Alonso; Jorginho, Kante, Kovacic; Pedro, Morata, Hazard
Newcastle United XI (5-4-1): Dubravka; Yedlin, Schar, Fernandez, Clark, Dummett; Ritchie, Ki, Diame, Murphy; Rondon
Fulham XI (4-3-3): Bettinelli; Fosu-Mensah, Le Marchand, Odoi, Bryan; Seri, McDonald, Cairney; Vietto, Schurrle, Mitrovic
Burnley XI (4-5-1): Hart; Lowton, Tarkowski, Mee, Ward; Westwood, Cork, Gudmundsson, Lennon, Hendrick; Wood
