Kieran Trippier (£6.0m) could punish the 163,000+ managers who sold him for Gameweek 2 as he was handed his first start of the season against Fulham.
He remains the most popular Fantasy Premier League defender, with 22.2 percent ownership, even after missing out on Gameweek 1.
There is a full debut for Southampton’s Danny Ings (£5.5m) at Goodison Park, after he impressed in his cameo appearance at the end of Gameweek 1.
Hosts Everton went with Mason Holgate (£4.5m) at centre-back in the place of the suspended Phil Jagielka (£4.5m), while Leighton Baines (£5.5m) started at left-back once again.
Jonny Evans (£5.0m) is to make his bow in Leicester City colours today coming back from injury to replace Wes Morgan (£4.5m) in the starting line-up alongside Harry Maguire (£5.5m). Not surprisingly, Jamie Vardy (£9.0m) starts up front.
Ruben Neves (£5.1m) is Saturday’s most transferred in player with 388,000+ new owners, and he starts for Wolves at the King Power Stadium.
Bournemouth have named an unchanged XI for their trip to West Ham while Javier Hernandez (£6.5m) starts up front next to Marko Arnautovic (£7.0m).
EVERTON XI: Pickford; Baines, Holgate, Keane, Coleman; Schneiderlin, Gueye; Richarlison, Sigurdsson, Walcott; Tosun
SOUTHAMPTON XI: McCarthy, Cedric, Hoedt, Stephens, Bertrand, Romeu, Lemina, Ward-Prowse, Redmond, Austin, Ings
LEICESTER XI: Schmeichel; Chilwell, Maguire, Evans, Pereira; Mendy, Ndidi; Gray, Maddison, Albrighton; Vardy
WOLVES XI: Patricio; Bennett, Coady, Boly; Jonny, Neves, Moutinho, Doherty; Jota, Jimenez, Costa
SPURS XI: Lloris, Trippier, Alderweireld, Sanchez, Vertonghen, Davies, Dier, Eriksen, Lucas, Dele, Kane
FULHAM XI: Fabri, Fosu-Mensah, Chambers, Le Marchand, Bryan, Seri, Anguissa, Cairney, Kamara, Sessegnon, Mitrovic.
WEST HAM: Fabianski; Masuaku, Balbuena, Ogbonna, Zabaleta; Anderson, Noble, Wilshere, Snodgrass; Arnautovic, Chicharito.
BOURNEMOUTH: Begovic; Daniels, Aké, S Cook, A Smith; Fraser, Surman, Gosling, Brooks; King, Wilson
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5 years, 10 months agoGoal: Lucas Moura
Assist: Alexis Sanchez