Two Premier League matches kick off at 2pm BST today – Southampton v Manchester United and Wolverhampton Wanderers v Tottenham Hotspur.
Ole Gunnar Solskjaer makes two changes from the team that comfortably beat Leeds United in Gameweek 1, as Nemanja Matic (£4.5m) and Anthony Martial (£7.9m) replace Scott McTominay (£5.5m) and Daniel James (£6.0m) in the starting XI.
New signings Raphael Varane (£5.5m) and Jadon Sancho (£9.4m) are both named on the bench.
Ralph Hasenhüttl’s Southampton will be looking to bounce back from their opening-day loss at Everton, though they are without a win in 10 home league matches against The Red Devils.
New signing Adam Armstrong (£6.0m) leads the line, while £4.0m defender Tino Livramento gets another start at right-back ahead of Kyle Walker-Peters (£5.0m), who again has to settle for a place on the bench.
At Tottenham Hotspur, Nuno names an unchanged starting XI with Harry Kane (£12.4m) on the bench. That means another out-of-position start for Son Heung-min (£10.0m).
Of all the current Premier League sides that the South Korean international has played against, Wolves are the only team he hasn’t scored against. Could that be about to change?
Meanwhile, Bruno Lage takes charge of his first Wolves home game and makes just one change to his starting XI, with Nelson Semedo (£5.0m) replacing Ki-Jana Hoever (£4.0m).
GAMEWEEK 2 LINE-UPS
Southampton XI: McCarthy, Livramento, Stephens, Salisu, Perraud, Romeu, Ward-Prowse, Walcott, Djenepo, Adams, A Armstrong
Subs: Forster, Bednarek, Walker-Peters, Valery, Diallo, Elyounoussi, Tella, Redmond, Long
Man Utd XI: de Gea, Wan-Bissaka, Lindelof, Maguire, Shaw, Matic, Fred, Martial, Fernandes, Pogba, Greenwood
Subs: Heaton, Dalot, Varane, James, Lingard, Mata, McTominay, van de Beek, Sancho
Wolves XI: Sa, Kilman, Coady, Saiss, Semedo, Moutinho, Neves, Marcal, Trincao, Traore, Jimenez
Subs: Ruddy, Hoever, Ait-Nouri, Silva, Gibbs-White, Dendoncker, Cundle, Marques, Campbell
Spurs XI: Lloris, Tanganga, Sanchez, Dier, Reguilon, Hojbjerg, Skipp, Alli, Moura, Bergwijn, Son
Subs: Gollini, Doherty, Davies, Sessegnon, Winks, Lo Celso, Gil, Kane, Scarlett
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